Adaptive Laboratory Evolution
Evolving E. coli 498 under rising reaction-water pressure in continuous culture, tracking how tolerance and growth change run after run.
- Microbial adaptation
- Selection pressure
- E. coli 498
Elijá Friedrich-Ulrich
BSc Medical & Pharmaceutical Biotechnology · IMC Krems, Austria
I evolve bacteria to survive toxic industrial water, and write the code behind the experiments.
I run adaptive laboratory evolution experiments for the EcoCoat project and build the analysis tools and lab infrastructure around them.
Featured research
Teaching bacteria to feed on industrial reaction water
Adaptive laboratory evolution of E. coli 498 toward toxic paint and resin residues in reaction water, from morbidostat selection to validation with data and bioassays.
Read the research article
Research
Topic areas
My current work is microbial adaptation, industrial reaction water, and keeping the experiments reproducible.
All research
Research overviewIndustrial Reaction Water & Bioremediation
Toxic paint and resin residues from polyester resin production. I test whether the adapted cultures can use those compounds as a carbon source.
- Reaction water
- Carbon-source utilization
- Environmental biotechnology
Continuous Cultivation Systems
Running morbidostat experiments on the Replifactory, with automated dosing and OD600 feedback over long adaptation runs.
- Morbidostats
- Replifactory
- Automated experimental control
Selected work
Projects
A few things I am building or have finished, in the lab and in code.
All projects
All projectsOff the clock
Beyond the lab
Work outside the lab: field documentation, visual work, and the websites I build and host myself.
Fawn rescue
Using a drone with thermal and normal cameras to help find fawns in fields.
Drone photography
Aerial photos from my own flights — mostly forests and open country.
Website building
Designing, building, self-hosting, and iterating personal websites and small digital systems — including this portfolio.