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Research

Research overview

I study whether microbial adaptation can turn a toxic industrial waste stream into something biologically treatable — and how to measure that change rigorously.

Adaptive Laboratory Evolution

Evolving E. coli 498 under rising reaction-water pressure in continuous culture, tracking how tolerance and growth change run after run.

  • Microbial adaptation
  • Selection pressure
  • E. coli 498
Read the ALE article

Industrial Reaction Water & Bioremediation

Toxic paint and resin residues from polyester resin production. I test whether the adapted cultures can use those compounds as a carbon source.

  • Reaction water
  • Carbon-source utilization
  • Environmental biotechnology
Problem and approach

Continuous Cultivation Systems

Running morbidostat experiments on the Replifactory, with automated dosing and OD600 feedback over long adaptation runs.

  • Morbidostats
  • Replifactory
  • Automated experimental control
Morbidostat workflow

Ecotoxicity & Validation

Ongoing

Setting up Microtox bioassays with Aliivibrio fischeri to check whether biological treatment lowers acute toxicity. Work in progress.

  • Microtox
  • Aliivibrio fischeri
  • Toxicity reduction
Validation approach

Research Data & Reproducibility

Python pipelines for time-series analysis and structured lab records in eLabFTW, so experiments stay traceable from raw data to figures.

  • Python analysis
  • Time-series processing
  • eLabFTW
Data & tooling projects