Adaptive Laboratory Evolution
Evolving E. coli 498 under increasing reaction-water pressure in continuous culture, tracking tolerance and growth dynamics across iterative runs.
- Microbial adaptation
- Selection pressure
- E. coli 498
Research
Research overview
I study whether microbial adaptation can turn a toxic industrial waste stream into something biologically treatable — and how to measure that change rigorously.
Industrial Reaction Water & Bioremediation
Working with toxic paint and resin residues from polyester resin production — testing whether adapted cultures can use those compounds as a carbon source.
- Reaction water
- Carbon-source utilization
- Environmental biotechnology
Continuous Cultivation Systems
Running morbidostat experiments on the Replifactory with automated dosing, OD600 feedback, and long-running adaptation campaigns.
- Morbidostats
- Replifactory
- Automated experimental control
Ecotoxicity & Validation
OngoingSetting up Microtox ecotoxicity bioassays with Aliivibrio fischeri to ask whether biological treatment reduces acute toxicity — work in progress.
- Microtox
- Aliivibrio fischeri
- Toxicity reduction
Research Data & Reproducibility
Python pipelines for time-series analysis, structured lab documentation in eLabFTW, and workflows that keep experiments traceable from raw data to figures.
- Python analysis
- Time-series processing
- eLabFTW